{"$schema": "https://iptc.org/std/ninjs/ninjs-schema_3.2.json", "uri": "urn:newsml:wireva.mib.news:story:0531d9c4-1ac1-4e6f-863f-ac94f0581ffb", "type": "composite", "version": "1", "versioncreated": "2026-08-23T10:03:42.932036Z", "firstcreated": "2026-08-23T10:03:42.932036Z", "pubstatus": "usable", "language": "en", "headline": "Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "description_text": "Researchers at King's College London identified a new therapeutic mechanism for heart failure with preserved ejection fraction (HFpEF), a condition affecting nearly half of all heart failure patients. The natural postbiotic compound urolithin A may offer a new treatment avenue for this previously resistant condition.", "associations": {"item-0": {"$schema": "https://iptc.org/std/ninjs/ninjs-schema_3.2.json", "uri": "urn:newsml:wireva.mib.news:item:07b0f17d-5956-4074-ac8c-768247fc3448", "type": "text", "profile": "standard", "version": "1", "versioncreated": "2026-08-23T10:08:33.254001Z", "firstcreated": "2026-08-23T10:03:42.932036Z", "pubstatus": "usable", "urgency": 5, "language": "en", "headline": "Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "byline": "Jenna Mercer", "located": "United States", "copyrightholder": "Haydamax OÜ", "copyrightnotice": "Wireva / Science Official", "usageterms": "Monitoring item. Headline, short extract and the source link may be shown. Do not republish the full text.", "description_text": "Researchers at King's College London identified a new therapeutic mechanism for heart failure with preserved ejection fraction (HFpEF), a condition affecting nearly half of all heart failure patients. The natural postbiotic compound urolithin A may offer a new treatment avenue for this previously resistant condition.", "altids": {"mosaic": "07b0f17d-5956-4074-ac8c-768247fc3448", "story": "0531d9c4-1ac1-4e6f-863f-ac94f0581ffb", "slug": "postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure"}, "subject": [{"name": "Health", "rel": "direct", "literal": "health", "code": "medtop:07000000", "scheme": "http://cv.iptc.org/newscodes/mediatopic/", "uri": "http://cv.iptc.org/newscodes/mediatopic/07000000"}], "place": [{"name": "United States", "literal": "us", "code": "US", "scheme": "http://cv.iptc.org/newscodes/countrycodes/"}], "person": [], "organisation": [], "genre": [{"name": "Standard story", "literal": "standard"}], "service": [{"name": "Wireva", "literal": "wireva"}], "body_text": "Researchers at King's College London identified a new therapeutic mechanism for heart failure with preserved ejection fraction (HFpEF), a condition affecting nearly half of all heart failure patients. The natural postbiotic compound urolithin A may offer a new treatment avenue fo", "extra_body_note": "Extract only — see rights.class = link_only.", "associations": {"featuremedia": {"uri": "urn:newsml:wireva.mib.news:media:2779fe4a-cf3a-458d-9aa3-906f6f38d451", "type": "picture", "version": "1", "pubstatus": "usable", "headline": "Natural Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "description_text": "Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "copyrightholder": "cdn.sci.news", "copyrightnotice": "Natural Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "usageterms": "Picture belongs to the source publication: address and terms are delivered, the file is not.", "altids": {"wireva": "2779fe4a-cf3a-458d-9aa3-906f6f38d451"}, "extra": {"wireva:delivery_mode": "link_only", "wireva:rights": {"licence": "", "licence_url": "", "licence_raw": "RSS source", "licence_verified_at": "2026-08-23T10:08:33.278608Z", "attribution_required": true, "attribution_text": "Natural Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "redistribution_allowed": false, "commercial_use_allowed": false, "modifications_allowed": false, "share_alike_required": false}, "wireva:provenance": {"creator": "", "source_name": "cdn.sci.news", "source_url": "https://cdn.sci.news/images/2026/08/image_15008f-Pomegranate.jpg", "source_page_url": "https://cdn.sci.news/images/2026/08/image_15008f-Pomegranate.jpg", "our_page_url": "https://scienceofficial.org/medicine/postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure/"}, "wireva:role": "lead"}, "renditions": {"source": {"href": "https://cdn.sci.news/images/2026/08/image_15008f-Pomegranate.jpg", "mimetype": "image/jpeg"}}}}, "extra": {"wireva:story": {"uri": "urn:newsml:wireva.mib.news:story:0531d9c4-1ac1-4e6f-863f-ac94f0581ffb", "slug": "postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure-20260823", "status": "developing", "languages": ["en"], "item_count": 1, "is_breaking": false}, "wireva:rights": {"class": "link_only", "redistribution_allowed": false, "commercial_use_allowed": false, "modifications_allowed": true, "share_alike_required": false, "attribution_required": true, "attribution_text": "Wireva / Science Official", "canonical_required": true, "canonical_url": "https://scienceofficial.org/medicine/postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure/", "linkback_required": true, "licence": "", "licence_url": "", "licensor": "Haydamax OÜ", "valid_until": null, "excerpt_max_chars": 280, "decided_by_rule": "derivation_failed", "needs_review": true}, "wireva:provenance": {"production_method": "automated", "ai_stages": {"editing": true, "drafting": true, "headline": true, "discovery": true, "classification": true, "image_selection": true, "source_collection": true, "cross_source_comparison": true}, "model": "", "human_reviewed": false, "reviewed_by": "", "reviewed_at": null, "editorial_control": true, "editorial_responsibility": "Haydamax OÜ (Wireva)", "factchecked": false, "verification_status": "single_source", "independent_confirmations": 0, "official_source_used": false, "used_press_release": false, "public_interest": true, "ai_disclosure_required": true, "ai_disclosure_text": "This item was produced with AI assistance under the editorial responsibility of Haydamax OÜ.", "independence_check": {"status": "failed", "score": 0.805, "checked_at": "2026-08-23T10:08:33.274120Z"}, "sources": [{"url": "https://www.sci.news/medicine/urolithin-a-heart-failure-with-preserved-ejection-fraction-15008.html", "title": "Natural Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure", "publisher": "sci.news", "type": "rss", "role": "primary", "official": false, "retrieved_at": "2026-08-23T10:08:33.260445Z", "published_at": "2026-08-21T20:55:12Z"}]}, "wireva:publication": {"name": "Science Official", "domain": "scienceofficial.org", "country": "US", "url": "https://scienceofficial.org/medicine/postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure/"}, "wireva:links": {"self": "https://wireva.mib.news/api/v1/items/07b0f17d-5956-4074-ac8c-768247fc3448", "html": "https://wireva.mib.news/item/07b0f17d-5956-4074-ac8c-768247fc3448/postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure/", "story": "https://wireva.mib.news/story/postbiotic-compound-shows-promise-against-hard-to-treat-heart-failure-20260823/"}, "wireva:metrics": {"word_count": 629, "char_count": 4218, "reading_time_seconds": 301}}}}, "extra": {"wireva:languages": ["en"], "wireva:status": "developing", "wireva:item_count": 1}}