{"$schema": "https://iptc.org/std/ninjs/ninjs-schema_3.2.json", "uri": "urn:newsml:wireva.mib.news:story:08a6ac7c-915e-4875-9caf-b6813c3acfe4", "type": "composite", "version": "1", "versioncreated": "2026-08-29T13:03:21.416832Z", "firstcreated": "2026-08-29T13:03:21.416832Z", "pubstatus": "usable", "language": "en", "headline": "Potent antiplatelet drugs raise bleeding risk in atrial fibrillation patients", "description_text": "A randomized trial presented at the 2026 European Society of Cardiology Congress found that combining direct oral anticoagulants with potent P2Y12 inhibitors in atrial fibrillation and acute coronary syndrome patients increased bleeding without reducing ischemic events, compared to clopidogrel and aspirin.", "associations": {"item-0": {"$schema": "https://iptc.org/std/ninjs/ninjs-schema_3.2.json", "uri": "urn:newsml:wireva.mib.news:item:bc58f4ab-727b-4af3-8d7b-592f80c62322", "type": "text", "profile": "standard", "version": "1", "versioncreated": "2026-08-29T13:03:34.518932Z", "firstcreated": "2026-08-29T13:03:21.416832Z", "pubstatus": "usable", "urgency": 5, "language": "en", "headline": "Potent antiplatelet drugs raise bleeding risk in atrial fibrillation patients", "byline": "Logan Weston", "located": "United States", "copyrightholder": "Haydamax OÜ", "copyrightnotice": "Wireva / Science Official", "usageterms": "Subscribers may republish this item in full, including translation and trimming, with the credit “Wireva / Science Official”. Set rel=canonical to https://scienceofficial.org/medicine/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients/ when publishing on the web.", "description_text": "A randomized trial presented at the 2026 European Society of Cardiology Congress found that combining direct oral anticoagulants with potent P2Y12 inhibitors in atrial fibrillation and acute coronary syndrome patients increased bleeding without reducing ischemic events, compared to clopidogrel and aspirin.", "altids": {"mosaic": "bc58f4ab-727b-4af3-8d7b-592f80c62322", "story": "08a6ac7c-915e-4875-9caf-b6813c3acfe4", "slug": "potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients"}, "subject": [{"name": "Health", "rel": "direct", "literal": "health", "code": "medtop:07000000", "scheme": "http://cv.iptc.org/newscodes/mediatopic/", "uri": "http://cv.iptc.org/newscodes/mediatopic/07000000"}], "place": [{"name": "United States", "literal": "us", "code": "US", "scheme": "http://cv.iptc.org/newscodes/countrycodes/"}], "person": [], "organisation": [], "genre": [{"name": "Standard story", "literal": "standard"}], "service": [{"name": "Wireva", "literal": "wireva"}], "associations": {"featuremedia": {"uri": "urn:newsml:wireva.mib.news:media:44987ed1-5d61-40a6-a6ac-ceb815cde0a0", "type": "picture", "version": "1", "pubstatus": "usable", "headline": "Dual antithrombotic therapy using potent antiplatelet inhibitors in atrial fibrillation and acute coronary syndrome: a randomized controlled trial", "description_text": "Potent antiplatelet drugs raise bleeding risk in atrial fibrillation patients", "copyrightholder": "commons.wikimedia.org", "copyrightnotice": "Macro987", "usageterms": "Public domain work (government or dedicated). Credit appreciated, not required.", "altids": {"wireva": "44987ed1-5d61-40a6-a6ac-ceb815cde0a0"}, "extra": {"wireva:delivery_mode": "file", "wireva:rights": {"licence": "Public domain", "licence_url": "https://creativecommons.org/publicdomain/mark/1.0/", "licence_raw": "Public domain", "licence_verified_at": "2026-08-29T13:03:34.533435Z", "attribution_required": false, "attribution_text": "Macro987", "redistribution_allowed": true, "commercial_use_allowed": true, "modifications_allowed": true, "share_alike_required": false}, "wireva:provenance": {"creator": "", "source_name": "commons.wikimedia.org", "source_url": "https://commons.wikimedia.org/wiki/File:Cubeholter.jpg", "source_page_url": "https://commons.wikimedia.org/wiki/File:Cubeholter.jpg", "our_page_url": "https://scienceofficial.org/medicine/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients/"}, "wireva:role": "lead"}, "renditions": {"original": {"href": "https://nbg1.your-objectstorage.com/ckln/image-assets/d451a49bd2a7bc1f353ae027ccd48e15cec87bfc59e6ad1a2d3b5eb01d535880.jpg", "mimetype": "image/jpeg", "width": 1024, "height": 742, "sizeinbytes": 161837}, "source": {"href": "https://commons.wikimedia.org/wiki/File:Cubeholter.jpg", "mimetype": "image/jpeg"}}}}, "extra": {"wireva:story": {"uri": "urn:newsml:wireva.mib.news:story:08a6ac7c-915e-4875-9caf-b6813c3acfe4", "slug": "potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients-20260829", "status": "closed", "languages": ["en"], "item_count": 1, "is_breaking": false}, "wireva:rights": {"class": "agency_original", "redistribution_allowed": false, "commercial_use_allowed": false, "modifications_allowed": true, "share_alike_required": false, "attribution_required": true, "attribution_text": "Wireva / Science Official", "canonical_required": true, "canonical_url": "https://scienceofficial.org/medicine/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients/", "linkback_required": true, "licence": "", "licence_url": "", "licensor": "Haydamax OÜ", "valid_until": null, "excerpt_max_chars": 0, "decided_by_rule": "agency_original_borderline", "needs_review": true}, "wireva:provenance": {"production_method": "automated", "ai_stages": {"editing": true, "drafting": true, "headline": true, "discovery": true, "classification": true, "image_selection": true, "source_collection": true, "cross_source_comparison": true}, "model": "", "human_reviewed": false, "reviewed_by": "", "reviewed_at": null, "editorial_control": true, "editorial_responsibility": "Haydamax OÜ (Wireva)", "factchecked": false, "verification_status": "single_source", "independent_confirmations": 0, "official_source_used": false, "used_press_release": false, "public_interest": true, "ai_disclosure_required": true, "ai_disclosure_text": "This item was produced with AI assistance under the editorial responsibility of Haydamax OÜ.", "independence_check": {"status": "borderline", "score": 0.375, "checked_at": "2026-08-29T13:03:34.530866Z"}, "sources": [{"url": "https://www.nature.com/articles/s41591-026-04629-7", "title": "Briefing Chat: How Dolly Parton left her mark on science", "publisher": "nature.com", "type": "rss", "role": "primary", "official": false, "retrieved_at": "2026-08-29T13:03:34.523937Z", "published_at": "2026-08-27T23:00:00Z"}, {"url": "https://www.nature.com/articles/d41586-026-02732-w", "title": "", "publisher": "nature.com", "type": "rss", "role": "supporting", "official": false, "retrieved_at": "2026-08-29T13:03:34.521291Z", "published_at": null}]}, "wireva:publication": {"name": "Science Official", "domain": "scienceofficial.org", "country": "US", "url": "https://scienceofficial.org/medicine/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients/"}, "wireva:links": {"self": "https://wireva.mib.news/api/v1/items/bc58f4ab-727b-4af3-8d7b-592f80c62322", "html": "https://wireva.mib.news/item/bc58f4ab-727b-4af3-8d7b-592f80c62322/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients/", "story": "https://wireva.mib.news/story/potent-antiplatelet-drugs-raise-bleeding-risk-in-atrial-fibrillation-patients-20260829/"}, "wireva:metrics": {"word_count": 540, "char_count": 3882, "reading_time_seconds": 277}}}}, "extra": {"wireva:languages": ["en"], "wireva:status": "closed", "wireva:item_count": 1}}