A multicenter analysis of clinical trial samples from non-Hodgkin lymphoma patients found that a high proportion of naive-like and stem cell memory-like CCR7+CD45RA+ T cells in the pre-infusion CAR T product is linked to improved and prolonged clinical benefit, a finding validat…
T Cell Profile in CAR T Products Predicts Lymphoma Response, Study Finds
A multicenter analysis of clinical trial samples from non-Hodgkin lymphoma patients found that a high proportion of naive-like and stem cell memory-like CCR7+CD45RA+ T cells in the pre-infusion CAR T product is linked to improved and prolonged clinical benefit, a finding validated in an independent external cohort.
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