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Scientists Observe Virus-Like Particle Assembly at Molecular Level in Real Time

Researchers have achieved real-time, molecular-resolution monitoring of individual virus-like particles as they self-assemble, using mass photometry combined with a single-molecule trapping method. The technique reveals assembly pathways and dynamics that were previously inaccessible, with implications for drug delivery, vaccine design, and understanding viral infection.

Molecular-level observation of the self-assembly of a virus-like particle
Scientists Observe Virus-Like Particle Assembly at Molecular Level in Real Time
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Researchers have achieved real-time, molecular-resolution monitoring of individual virus-like particles as they self-assemble, using mass photometry combined with a single-molecule trapping method. The technique reveals assembly pathways and dynamics that were previously inacces…